CRN Monthly Update for November/December 2014

In this issue:

Highlights

Hazel Nichols, PhD, assistant professor of epidemiology at UNC Gillings School of Global Public Health and a CRN Scholar was recently awarded $200,000External Web Site Policy for work related to pregnancy-associated breast cancer at the Avon Walk for Breast Cancer in Charlotte. Congratulations Hazel!

The CRN would like to announce that Matt Nielsen MD, Assistant Professor of Urology at the UNC School of Medicine, has been appointed as a Clinical Investigator at KPNW Center for Health Research. Matt is currently a co-investigator on a CRN Pilot Study using data from KPNW to analyze changes in treatment technology for prostate cancer over time. Additionally, Carmit McMullen, PhD, a medical anthropologist who studies health care delivery, cancer survivorship, and aging and Matt have collaborated on the development of a concept exploring risk stratification and decision support for the care of patients with superficial bladder cancer; they submitted an R21 proposal for this as co-PIs.

At its December 7 meeting, The PCORI Board of Governors approved up to $50 millionExternal Web Site Policy to fund comparative effectiveness research in hepatitis C virus, a liver cancer risk factor. They also approved up to $150.7 million for the next phase of PCORnet, their national health data network initiative.

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Recent CRN-Related Publications

Han PK, Williams AE, Haskins A, Gutheil C, Lucas FL, Klein WM, Mazor KM. Individual differences in aversion to ambiguity regarding medical tests and treatments: association with cancer screening cognitions. Cancer Epidemiol Biomarkers Prev 2014 Dec;23(12):2916-23. [View Abstract]

Mazor KM, Williams AE, Roblin DW, Gaglio B, Cutrona SL, Costanza ME, Han PK, Wagner JL, Fouayzi H, Field TS. Health literacy and pap testing in insured women. J Cancer Educ 2014 Dec;29(4):698-701. doi: 10.1007/s13187-014-0629-7. [View Abstract]

Sivaram S, Sanchez MA, Rimer BK, Samet JM, Glasgow RE. Implementation Science in Cancer Prevention and Control: A Framework for Research and Programs in Low- and Middle-Income Countries. Cancer Epidemiol Biomarkers Prev 2014 Nov;23(11):2273-2284. Review. [View Abstract]

Alfano CM, Smith T, de Moor JS, Glasgow RE, Khoury MJ, Hawkins NA, Stein KD, Rechis R, Parry C, Leach CR, Padgett L, Rowland JH. An action plan for translating cancer survivorship research into care. J Natl Cancer Inst 2014 Sep 22;106(11). pii: dju287. Print 2014 Nov. [View Abstract]

Rosenberg DE, Lee IM, Young DR, Prohaska TR, Owen N, Buchner DM. Novel Strategies for Sedentary Behavior Research. Med Sci Sports Exerc 2014 Sep 12. [Epub ahead of print] [View Abstract]

Kehl KL, Arora NK, Schrag D, Ayanian JZ, Clauser SB, Klabunde CN, Kahn KL, Fletcher RH, Keating NL. Discussions about clinical trials among patients with newly diagnosed lung and colorectal cancer. J Natl Cancer Inst 2014 Sep 13;106(10). pii: dju216. Print 2014 Oct. [View Abstract]

Sprague BL, Gangnon RE, Burt V, Trentham-Dietz A, Hampton JM, Wellman RD, Kerlikowske K, Miglioretti DL. Prevalence of mammographically dense breasts in the United States. J Natl Cancer Inst 2014 Sep 12;106(10). pii: dju255. Print 2014 Oct. [View Abstract]

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The CRN wants to hear from you!

You can share your comments, suggestions, feedback, praise, or anything else, anonymously via our Web site.

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Scientific Working Group Updates

Communication & Dissemination

Bridget Gaglio (Program Officer, PCORI) joined our October group teleconference to review the new PCORI Communication and Dissemination RFA. Bridget highlighted important components of the announcement and described strategies for successful applications.

During our November group teleconference, Carmit McMullen presented initial work on her Pilot Project that aims to promote provider endorsement of the HPV vaccination. The group offered valuable feedback and suggested industries that have faced analogous challenges. Erin Hahn also spoke about her experience as a fellow in the Mentored Training for Dissemination and Implementation Research in Cancer program.

Contact Vanessa Neergheen for more information on the C&D SWG.

Epidemiology of Prognosis & Outcomes

Christine Johnson and her team presented a webinar titled, "Advantages & Obstacles in Conducting a Successful Multi-Site Study within the CRN." We hope to have these very useful slides available on our Web site in the near future.

Contact Sarah Madrid for information on the EPO SWG.

Health Care Quality & Cost

Contact Joanna Bulkley for more information on the HCQC SWG.

Prevention & Screening

December 15, 12 PT - WEBINAR: Research priorities and funding opportunities for prevention & screening among cancer survivors, presented by Dr. Julia Rowland.

Please contact Tracy Becerra for more information on P&S SWG activities.

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Calls for Abstracts

2015 ASCO Annual MeetingExternal Web Site Policy - Abstracts due Februray 3, 2015

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Research Resources

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Additional Funding Opportunities

NCI-funded Post-Doctoral Training Opportunity in Implementation Science

Application deadline February 15, 2015

PRACCTISExternal Web Site Policy is a full-time NCI-funded post-doctoral fellowship training program designed to provide the next generation of cancer prevention and control researchers with the knowledge and skill sets to eliminate gaps in the translation of research to practice along the cancer continuum, including prevention of disease, early detection, diagnosis, treatment and survivorship.

This 2-3 year program emphasizes didactic training in implementation science and mentored research opportunities and provides access to a wide array of training and enrichment opportunities on the UMass Medical School campus. We emphasize training independent investigators who will become leaders in cancer prevention and control implementation science research.

Mentored Training for Dissemination and Implementation Research in Cancer (MT-DIRC)

Application Submission Deadline is January 16, 2015

If you wish to join an exciting learning collaborative of dissemination and implementation (D&I) researchers, we invite you to apply to our new program entitled: Mentored Training for Dissemination and Implementation Research in Cancer (MT-DIRC). Funded by a five year grant from the National Cancer Institute, this unique education program is positioned to build capacity in D&I research in cancer prevention and control. The MT-DIRC is first of its kind for post-doctoral scholars (fellows)—primarily individuals in early careers who want to pursue D&I research in cancer. This program will place strong emphasis on mentoring, applying competencies and curriculum specifically focused on cancer disparities, and working with a diverse set of partners. For details see the full announcementExternal Web Site Policy. Please e-mail us if you have any questions.

*** In addition, the CRN will support expenses for one additional fellow to participate in the MT-DIRC. This individual must be employed at a NCI-funded CRN Site and accepted into the program following procedures noted above. For further information, e-mail us.

HCSRN-OAICs AGING Initiative Pilot Project Announcement

Application submission deadline Jan 15, 2015

The goal of the HCSRN-OAICs AGING Initiative is to bridge the Health Care Systems Research Network (HCSRN) with the Claude D. Pepper Older Americans Independence Centers (OAICs) to create a national resource to nurture and advance an interdisciplinary research agenda focused on older adults with multiple chronic conditions (MCCs). These efforts will lay the foundation to address the knowledge gaps that exist regarding the health and healthcare of these understudied patients.

The HCSRN-OAICs AGING Initiative includes a Pilot Projects program led by Dr. Rebecca Silliman from the Boston Pepper Center and Dr. Mark Hornbrook from Kaiser Permanente Center for Health Research. One of the crucial requirements for these applications is that an application must include collaborating investigators from both an HCSRN research center and a Pepper Center.

Please review the full RFAExternal Web Site Policy. If you have any questions about the Pilot Projects Program or the HCSRN-OAICs AGING initiative, please address them to Kathryn Anzuoni.

RFA-MD-15-001: System-Level Health Services and Policy Research on Health Disparities (R01)

Application deadline January 20, 2015

The purpose of this Funding Opportunity Announcement (FOA) is to solicit innovative system-level health services and policy research that can directly and demonstrably contribute to the elimination of health disparities.

Find out more details.

RFA-CA-14-015: The Early Detection Research Network: Clinical Validation Centers (U01)

Letter of Intent Due - December 20, 2014

The EDRN is a national infrastructure funded to discover, develop, and validate biomarkers for risk assessment, detection, and molecular diagnosis and prognosis of early cancer. The proposed Clinical Validation Centerss will be responsible for clinical research on the validation of biomarkers.

Companion RFAs have also been released for Biomarker Developmental Laboratories, Biomarker Reference Laboratories, and a Data Management and Coordinating Center. Visit the Web site for further details regarding the Clinical Validation Centers.

RFA-ES-14-012: Environmental Influences during Windows of Susceptibility in Breast Cancer Risk (U01)

Letter of Intent Due - December 28, 2014

The overarching goal of the Breast Cancer and the Environment Research Program (BCERP) is to support integrated scientific research to enhance our knowledge of environmental and genetic factors underlying breast cancer risk. This funding opportunity will support transdisciplinary research projects to investigate the influence of environmental exposures during specific time windows of susceptibility on breast cancer risk. A companion RFA for a Coordinating Center has also been released. Visit the Web site for further details.

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Employment Opportunities

National Cancer Institute - Senior Scientist for Surveillance ResearchExternal Web Site Policy

The National Cancer Institute (NCI), is conducting a national search for a senior scientist to work within the Surveillance Research Program (SRP). SRP supports population-based cancer research to provide a quantitative portrait of cancer in the US population and to understand the factors influencing the cancer burden in specific populations.

Group Health Research Institute - Faculty Position in BiostatisticsExternal Web Site Policy

Group Health Research Institute (GHRI) is seeking an experienced doctorate-level faculty member in biostatistics to collaborate on multidisciplinary research teams and lead independent methods research in a setting with access to rich electronic health care data.

Two Year Post-Doctoral Fellowship Opportunity in Cancer Epidemiology. Henry Ford Hospital - Josephine Ford Cancer Institute

The Department of Public Health Sciences within the Henry Ford Hospital (HFH) and the Josephine Ford Cancer Institute in Detroit, Michigan invites applications for a post-doctoral fellow position, available immediately, within our active Cancer Epidemiology research group. We have ongoing research in prostate, breast, ovarian, lung and colon cancer. Resources include an electronic medical record and patient databases in place for over 20 years, and a frozen tissue biorepository with specimen collection over the past 15 years.

We seek talented and motivated candidates who plan to begin or expand their research career as a cancer epidemiologist and who wish to play a leading role on projects focused on molecular epidemiology research of patients conducted within the large diverse HFH patient population.

Candidates must hold a PhD in epidemiology, bioinformatics, biostatistics or related discipline. Some molecular biology laboratory experience is desired, but not required.

Please address inquiries to Dr. Benjamin Rybicki.

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