CRN Monthly Update for July 2014

In this issue:

Message from the Coordinating Center

The CRN recently completed the review for the 2014 Pilot Projects. The expectation is that these Pilot Projects will lead to fundable research applications or proposals. We are very pleased to announce this year's recipients, which are listed below. Six projects, covering a range of topics and cancers, will be funded.


-Larry, Heather & Melissa

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June 2014 Dates of Note

July 14: Scholars Program RFA to be distributed.

July 22: KPNC Site Visit.

July 24-25: KPSC Site Visit.

July 31: Scholars Program Applicant Webinar.

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Recent CRN-Related Publications

Wendel CS, Grant M, Herrinton L, Temple LK, Hornbrook MC, McMullen CK, Bulkley JE, Altschuler A, Krouse RS. Reliability and validity of a survey to measure bowel function and quality of life in long-term rectal cancer survivors. Qual Life Res 2014 Jun 3. [Epub ahead of print] [View Abstract]

Houssami N, Abraham LA, Onega T, Collins LC, Sprague BL, Hill DA, Miglioretti DL. Accuracy of screening mammography in women with a history of lobular carcinoma in situ or atypical hyperplasia of the breast. Breast Cancer Res Treat 2014 Jun;145(3):765-73. [View Abstract]

Chubak J, Aiello Bowles EJ, Tuzzio L, Ludman E, Rutter CM, Reid RJ, Wagner EH. Perspectives of cancer survivors on the role of different healthcare providers in an integrated delivery system. J Cancer Surviv 2014 Jun;8(2):229-38. [View Abstract]

Sun V, Grant M, McMullen CK, Altschuler A, Mohler MJ, Hornbrook MC, Herrinton LJ, Krouse RS. From diagnosis through survivorship: health-care experiences of colorectal cancer survivors with ostomies. Support Care Cancer 2014 Jun;22(6):1563-70. [View Abstract]

Onega T, Hubbard R, Hill D, Lee CI, Haas JS, Carlos HA, Alford-Teaster J, Bogart A, DeMartini WB, Kerlikowske K, Virnig BA, Buist DS, Henderson L, Tosteson AN. Geographic Access to Breast Imaging for US Women. J Am Coll Radiol 2014 May 30. pii: S1546-1440(14)00161-6. [Epub ahead of print] [View Abstract]

Stout NK, Lee SJ, Schechter CB, Kerlikowske K, Alagoz O, Berry D, Buist DS, Cevik M, Chisholm G, de Koning HJ, Huang H, Hubbard RA, Miglioretti DL, Munsell MF, Trentham-Dietz A, van Ravesteyn NT, Tosteson AN, Mandelblatt JS. Benefits, harms, and costs for breast cancer screening after US implementation of digital mammography. J Natl Cancer Inst 2014 May 28;106(6):dju092. Print 2014 Jun. [View Abstract]

Trentham-Dietz A, Sprague BL, Hampton JM, Miglioretti DL, Nelson HD, Titus LJ, Egan KM, Remington PL, Newcomb PA. Modification of breast cancer risk according to age and menopausal status: a combined analysis of five population-based case-control studies. Breast Cancer Res Treat 2014 May;145(1):165-75. [View Abstract]

Potosky AL, Haque R, Cassidy-Bushrow AE, Ulcickas Yood M, Jiang M, Tsai HT, Luta G, Keating NL, Smith MR, Van Den Eeden SK. Effectiveness of primary androgen-deprivation therapy for clinically localized prostate cancer. J Clin Oncol 2014 May 1;32(13):1324-30. [View Abstract]

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Scientific Working Group Updates

Communication & Dissemination

Gloria Coronado (KPNW) presented a systems-based approach to understanding variation in clinic workflows during the June SWG teleconference. Using this approach, Dr. Coronado documented clinic workflows for colorectal cancer screening and follow-up in a large multi-site pragmatic study involving community health centers.

Kathy Mazor met with Rosalie Torres Stone and Carl Fulwiler, both of the University of Massachusetts Medical School (UMMS), to discuss potential CRN collaboration surrounding mindfulness in cancer treatment and survivorship and anti-depressant-related medication issues. Kathy also spoke with Stephanie Lemon and Tom Houston (also of UMMS) about a grant they recently received to lead an implementation research training program in cancer prevention and control at UMMS.

Two C&D co-leads, Brian Mittman and Russ Glasgow, are expecting to represent the CRN at the NIH's upcoming 7th Annual Conference on the Science of Dissemination and Implementation on December 8 and 9.

Contact Vanessa Neergheen for information on how to join upcoming calls.

Epidemiology of Prevention & Screening

Elizabeth Loggers is in discussion with Sam Hanash of MD Anderson regarding involvement in a serum based biomarkers "Think Tank". These Think Tank discussions are meant to engage successful, senior investigators by inviting them to learn about the CRN and brainstorm how CRN scientific and data resources could be used to advance science.

David Carrell, an investigator at GHRI and a CRN Pilot Project recipient will present to the SWG on Sept 9th, 2014 on Natural Language Processing methods.

Michelle Wrenn has stepped down as the Project Manager for this SWG. Future inquiries or communications should be directed to Sarah Madrid. Thank you for all your hard work Michelle, and welcome Sarah!

Health Care Quality & Cost

SWG leads recently met with Steven Chang, an oncologist at Henry Ford Health System, and Susan Snyder, a Health Economist at Geisinger Health System, who are hoping to develop a collaboration with the CRN. Initial conversations have focused on their interest in conducting a cost effectiveness analysis for head and neck cancers.

The rectal cancer team at KPNW which includes Mark Hornbrook, Carmit McMullen (former CRN Scholar), and Joanna Bulkley presented four posters at the 7th Biennial Cancer Survivorship Research Conference, June 18-20, 2014, Atlanta, GA. The rectal cancer team also received the Clinical Practice Manuscript Award from the Wound Ostomy and Continence Nurses Society.

Please contact Joanna Bulkley for more information on how to become involved with this SWG.

Prevention & Screening

The P&S SWG will be holding their 7th network teleconference on September 15, 2014, 12 pm Pacific. More information is forthcoming. Please contact Tracey Becerra for information on how to join this call.


The Informatics Core is working to increase the utility of CRNnet and is planning to use this tool to distribute SAS codes to two CRN Sites (KPNC and KPCO) for a test run. After further testing and implementation, this is expected to expedite the completion of prep-to-research requests.

Jessica Chubak attended and presented at the 7th Biennial Cancer Survivorship Research Conference, June 18-20, 2014, Atlanta, GA where she talked about the CRN as a platform for survivorship research. She provided information about data resources and discussed the advantages and opportunities of doing survivorship research in the CRN, future directions for survivorship research, as well as how to collaborate with the CRN, among other things.


The Scholars Leadership Team is gearing up for the second round of recruitment for the Scholars Program. An Informational Webinar for applicants will be held on Thursday, July 31 at 1:00 Pacific Time. Please contact Sarah McDonald for information on how to join this call.

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Calls for Abstracts

AACR's Frontiers in Cancer Prevention Research

due July 21, 2014

This annual conference will take place September 28 to October 1, 2014 in New Orleans, LA. It fosters collaborations between all disciplines of prevention research, accelerates the progression in the field of prevention research, and promotes awareness of the vital importance of cancer prevention in reducing cancer incidence and mortality. The theme for this year's conference is "From Cells to Society." Plenary sessions will be held on the microbiome, metabolism, and dietary prevention. All sessions will be cross-cutting and themes such as metabolism will be touched upon throughout the conference. Click hereExternal Web Site Policy for more information.

AACR's Science of Cancer Health Disparities on Racial/Ethnic Minorities and the Medically Underserved

due August 4, 2014

This conference takes place November 9-12, 2014 in San Antonio, TX. It brings together scientists and other professionals across a variety of disciplines to discuss the latest findings in the field in order to accelerate the elimination of cancer health disparities. Through promoting the exchange of novel ideas and information between a wide range of professionals from academia, industry, government, and the community, this conference maximizes the opportunity for bringing research on health disparities from bench to bedside to community, and back again. Please visit our Web site to view the full programExternal Web Site Policy.

Academy Health's Conference on the Science of Dissemination & Implementation: Transforming Health Systems to Optimize Individual and Population Health

due August 8, 2014

December 8-9, 2014 | Bethesda North Marriott Hotel & Conference Center Overall, the goal of Dissemination and Implementation Sciences is to promote and rigorously evaluate the impact of the integration of evidence-based approaches, into clinical and community settings via public health practice, healthcare delivery and healthcare policy. Dissemination and Implementation Sciences are also characterized by a focus on the roles of variations in implementation processes (how interventions are implemented) and context of dissemination (setting, population, economic drivers as examples) on heterogeneity of results.

The conference seeks novel research or conceptual papers that address any of the topics included above, with emphasis on empirical, data driven findings for how best to integrate evidence-based interventions within clinical and community settings and/or how to recast the nature or conduct of the research itself to make it more relevant and actionable in those settings. Please visit the Web siteExternal Web Site Policy for more information.

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Additional Funding Opportunities

Applications due Aug 12, 2014; Pre-applications due July 29

Dept of Defense Lung Cancer Research Program, Concept Award

The goal of the LCRP is to eradicate deaths from lung cancer to better the health and welfare of military service members, Veterans, their families, other military beneficiaries, and the American public. As such, the LCRP will support and integrate research from multiple disciplines for risk assessment, prevention, early detection, diagnosis, and treatment for the control and cure of lung cancer. To review the seven Areas of Emphasis and more, please see the full funding announcement (PDF) External Web Site Policy.

Applications due Sept 25, 2014; LOI due 30 days prior

Enabling Resources for Pharmacogenomics (R24)

This FOA supports critical enabling research resources that will accelerate new research discoveries and/or implementation of research discoveries in pharmacogenomics. A proposed research resource must meet an ascertained community demand and benefit the entire scientific field. The FOA will support activities that can be clearly and specifically defined, are optimally designed, have evaluative measures built-in, are judiciously staffed, have formed partnerships where appropriate, and ideally have a proven track record and a finite lifetime. The outcome of an enabling resource must be highly impactful in a demonstrable way. Full announcement here.

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Employment Opportunities

Applied Research Program's Outcomes Research Branch

Branch Chief, Outcomes Research Branch

The Chief of ORB oversees the research and research administration of the Branch, is responsible to and represents the Branch at higher administrative levels, serves as an expert consultant on cancer-related health outcomes and quality of care research to the NCI and NIH, in responding to inquiries from the U.S. Congress and other federal agencies, and to scientific and professional societies, academic research organizations, and other appropriate venues.
Full Announcement (PDF).External Web Site Policy

Senior Scientist for Cancer Care Delivery Research

NCI Community Oncology Research Program

The person serving in this position will have a unique opportunity to serve the NCI as a scientific leader providing direction and leadership in planning, coordinating, and guiding a program of cancer care delivery research.
Full Announcement (PDF).External Web Site Policy

Letters of interest and vitae may be submitted immediately to Samantha Williams.

Kaiser Permanente Colorado

Investigator in Biobank Development and Cancer Research

The Kaiser Permanente Colorado Institute for Health Research (IHR) is seeking outstanding applicants to participate in the development of a biospecimen repository for research and contribute to the growing need for expertise in cancer epidemiology and genomic research. Currently, Investigators from the IHR are working with other Kaiser Permanente regions to develop a national biobank for research. This position is for a junior-level investigator (equivalent to an academic instructor or assistant professor) to work with our experienced investigators in the areas of biobanking, cancer epidemiology and genomics research.
Full Announcement (PDF).External Web Site Policy

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