CRN Monthly Update for March 2014

In this issue:

Message from the Coordinating Center

Kudos from the Coordinating Center.

There has been a lot of activity around the CRN Pilot and Developmental Program in the last couple of months and we would like to extend our gratitude.

First, we would like to thank the current CRN Pilot and Developmental Project PIs. They presented their work and progress made on their projects thus far in a well-attended webinar on Tuesday, February 25. A wide variety of topics were discussed including end-of-life care among adolescents with cancer and how to use natural language processing to capture cancer-related information. The CRN project portfolio continues to benefit from these projects and we are excited to fund another round of Pilot and Developmental projects in the coming months. We were also very happy to see that some of our Advisory Board members, NCI colleagues, and a number of prospective Pilot Project applicants were able to join the webinar.

Second, a quick thanks to everyone who has been connecting with potential applicants for the next round of Pilot and Developmental Projects. We know that this requires a lot of time and effort, and it is greatly appreciated. You may also be asked to help in the review of the Letter of Intent submissions this month, or the Full Applications that are due May 16 - so thanks in advance.

Upcoming dates to note:
KPNW Site Visit: March 18th-19th
HCSRN Conference: March 31st-April 3rd

-Larry, Heather & Melissa

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Research Highlights

Each year, the NCI's Epidemiology and Genomics Research Program identifies research highlights based on 10 peer-reviewed manuscripts from EGRP grantees. These research highlights arise from recommendations and voting among EGRP staff, to identify those research findings that have the greatest potential for scientific or public health impact . Three of the ten papers that were selected were based on research grants that are conducted at least in part in CRN Sites. The papers include:

View EGRP's full list here.

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Scientific Working Group/Core Updates

Communication & Dissemination

The C&D SWG is finalizing plans for the Dissemination and Implementation Science Training Workshop we will host at the 2014 HCSRN Conference. A few spaces are still available. To register, please fill out this survey.External Web Site Policy

Epidemiology of Prognosis & Outcomes

A multiple-PI NCI application, "Diet and Lifestyle in a Prospective Study of Bladder Cancer Survivors," has been recommended for funding. The contact PI is Marilyn Kwan at KPNC, and the other PIs are Li Tang at the Roswell Park Cancer Institute and Larry Kushi at KPNC. Virginia Quinn is site PI for KPSC. The project aims to enroll approximately 1,800 women and men with bladder cancer to investigate the effects on recurrence of dietary factors, especially cruciferous vegetable intake, including interactions with polymorphisms in isothiocyanate-metabolizing genes and bladder cancer therapies.

Health Care Quality & Cost

The HCQC SWG and the CRN PI's office led a CRN-wide conference call related to proposal opportunities and options related to the PCORI Pragmatic Studies initiative. Specifically, the topic of "Comparing the effectiveness of specific features of health insurance on access to care, use of care, and other outcomes that are especially important to patients."


We have moved CRNnet to PopMedNet V3, which now allows us to start work on the SAS VDW querying capability developed as part of the SPAN project.

Prevention & Screening

The P&S SWG will be holding a webinar on Monday, March 17, 2014, 12 PM PT. Myles Cockburn from the Keck School of Medicine of the University of Southern California will be presenting on issues related to skin cancer screening - Webinar linkExternal Web Site Policy; Meeting password: crn4pands; Call-in toll-free number: 1-877-668-4490; Access code: 572 215 978.

Seven abstracts related to colorectal cancer screening were submitted by the COLOFIT study team and accepted for presentation at the Digestive Disease Week conference in Chicago, to be held on May 3-6, 2014.

In addition, we had a paper on adenoma detection rate in colorectal cancer screening accepted to the New England Journal of Medicine: Corley DA, et al. Physician adenoma detection rate and colorectal cancer risk and mortality.


The CRN Scholars are preparing draft proposals of various types (R01, 3 and 21 as well as K and ACS). We will hold a mock study section to review these proposals during our semi-annual in-person meeting on March 31 in Phoenix on the day preceding the HCSRN conference. CRN Steering Committee members were invited to participate on the review panel, and review assignments are in process. We expect these reviews to be of great assistance to the Scholars as they move into the next phase of the program and begin submitting applications for funding. Many thanks to the reviewers!

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Workshops & Trainings

AACR's Integrative Molecular Epidemiology Workshop
August 11-15, 2014, Boston, MA
Application deadline: Monday, April 14

Applications are now open for the Integrative Molecular Epidemiology WorkshopExternal Web Site Policy. This five-day workshop is designed to accelerate the training of the next generation of cancer researchers who must be well-skilled in the integration of biology and epidemiology in studies of etiology and outcome. Visit our Web site today to view the full program for this workshop. Space is limited, so apply today! The application deadline is Monday, April 14.

The workshop is primarily targeted toward molecular epidemiologists, but the materials are designed to also be appropriate for geneticists, statisticians, bioinformaticians, molecular biologists, physician scientists, and others who have completed basic course work in epidemiology.

Training Institute for Dissemination and Implementation Research in Health (TIDIRH)
July 21-25, 2014, Harvard University, Boston, MA
Application deadline: April 6, 2014

One of the most critical issues impeding improvements in public health today is the enormous gap between what we know can optimize health and healthcare and what actually gets implemented in every day practice. The science of dissemination and implementation (D&I) seeks to address this gap by understanding how to best ensure that evidence-based strategies to improve health and prevent disease are effectively delivered in clinical and public health practice.

Harvard University, with support from the National Institutes of Health (National Cancer Institute, National Institute of Mental Health, National Institute of Diabetes and Digestive and Kidney Diseases, National Heart, Lung, and Blood Institute, Office of Disease Prevention, and the Office of Behavioral and Social Sciences Research) and the U.S. Department of Veterans Affairs, is sponsoring this 5-day training institute to provide participants with a thorough grounding in conducting dissemination and implementation research in health. Faculty and guest lecturers will consist of leading experts (practitioners and teachers) in theory, implementation and evaluation approaches to D&I, creating partnerships and multi-level, transdisciplinary research teams, research design, methods and analyses appropriate for D&I investigations and conducting research at different and multiple levels of interventions (e.g., clinical, community, policy).

See the full announcement here (PDF) . To apply please visit their Web siteExternal Web Site Policy.

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Additional Funding Opportunities

Application Deadline: March 25, 2014 (LOI due 30 days prior)

National Cancer Institute

Application Deadline: April 1, 2014

American Cancer Society

Application Deadline: May 20, 2014; September 23, 2014 (LOI due 30 days prior)

National Cancer Institute

Application Deadline: June 10, 2014 (LOI due 30 days prior)

National Cancer Institute

Application Deadline: June 20, 2014 (LOI due 30 days prior)

National Cancer Institute

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CRN Calendar

All times listed are Pacific.

A calendar of upcoming events in March and April [D]

For detailed meeting information, contact

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