CRN 2015 Highlights

In case you missed them, here are a few highlights from work conducted across Cancer Research Network institutions this past year.

Publication Highlights

Here are several publications which showcase the spectrum of population studies being conducted at CRN institutions, from screening and cost of care, to adjuvant chemotherapy use and end-of-life care. Also highlighted is a recent publication describing the Scholars Program, which is the CRN's Training and Career Development Program.

Training and Career Development

The CRN Scholars Program provides the opportunity for early-stage investigators to learn about conducting cancer research in the integrated healthcare settings of the CRN.

Training in the Conduct of Population-Based Multi-Site and Multi-Disciplinary Studies: the Cancer Research Network's Scholars Program.External Web Site Policy

Screening

The CRN continues to make research contributions that inform the development and implementation of cancer screening strategies.

Variation in Adenoma Detection Rate and the Lifetime Benefits and Cost of Colorectal Cancer Screening: A Microsimulation Model.External Web Site Policy

Impact of continued mailed fecal tests in the patient-centered medical home: Year 3 of the Systems of Support to Increase Colon Cancer Screening and Follow-Up randomized trial.External Web Site Policy

Cancer Treatment and Outcomes

Studies looking at the use of cancer therapy outside the clinical trial setting often lack detailed information on dose or side effects. The CRN provides the opportunity to examine such questions that can inform care. These studies demonstrate the ability to follow patients during long-term follow-up in the CRN setting.

Impact of Chemotherapy Dosing on Ovarian Cancer Survival According to Body Mass Index.External Web Site Policy

Use of Bevacizumab in Community Settings: Toxicity Profile and Risk of Hospitalization in Patients With Advanced Non-Small-Cell Lung Cancer.External Web Site Policy

Preventive care receipt and office visit use among breast and colorectal cancer survivors relative to age- and gender-matched cancer-free controls.External Web Site Policy

End-of-Life Care Intensity Among Adolescent and Young Adult Patients With Cancer in Kaiser Permanente Southern California.External Web Site Policy

Recurrence Detection

Cancer recurrence is a principal outcome in studies of cancer prognosis, but is challenging to identify in observational studies. In order to identify recurrences for research purposes, several projects taking place in the CRN setting are exploring recurrence identification using data available in electronic medical records and other clinical databases.

An Electronic Health Record-based Algorithm to Ascertain the Date of Second Breast Cancer Events.External Web Site Policy

Detecting Lung and Colorectal Cancer Recurrence Using Structured Clinical/Administrative Data to Enable Outcomes Research and Population Health Management.External Web Site Policy

Health Communication

With research groups that are part of the healthcare systems of the CRN, we provide the opportunity to examine health communications issues that may impact quality of care.

Primary care physicians' willingness to disclose oncology errors involving multiple providers to patients.External Web Site Policy

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Recently Funded Grants

Pragmatic Trial of More versus Less Intensive Strategies for Active Surveillance of Patients with Small Pulmonary NodulesExternal Web Site Policy, funded by the PCORI. PI: Michael Gould (KPSC)

Identification of DNA Methylation Markers for Risk of Metastasis in Localized Prostate Cancer, funded by the NCI. PI: Chun Chao (KPSC)

Risk of Pediatric and Adolescent Cancer Associated with Medical Imaging, funded by the NCI. Multiple PIs: Rebecca Smith-Bindman, UCSF (contact), Diana Miglioretti (UC Davis); Marilyn Kwan (KPNC)

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