HER2+ breast cancer is an aggressive subtype commonly treated with trastuzumab, which is highly effective in reducing recurrence but associated with increased risk of cardiac events. Building upon an existing KPNC study with a retrospective cohort of 1,000 women, this study proposes a mixed methods design to assess care coordination practices between cardiology, oncology, and primary care physicians managing this patient population and examine the impact of coordination on patient management and risk of cardiac events. The initial study included women with non-metastatic disease diagnosed between 2005 and 2011 identified through KPNC cancer registry, BEACON, CAMMOLOT, and COPS chemotherapy databases. Quantitative data will be used to assess coordination practices between physicians and qualitative interviews among a subset of physicians will be used to understand barriers and challenges to coordination. Study findings will have implications for improving breast cancer care delivery.
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